Macromolecular Proton Fraction (MPF): Quantitative Myelin Mapping Technique for Neuroscience

News

First large-scale neuroscience study based on the fast MPF mapping method published in Neuroimage
  • May 17, 2021, 10:30 PM
  • yarnykh

Based on brain MPF maps from 146 adolescents, the protracted myelin development in cortical gray matter and subcortical white matter has been characterized as the function of age, gender, and puberty status.

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ISMRM “Live Q&A session” on Wednesday, August 12, 2020, 14:30 - 15:15 UTC.
  • Aug 9, 2020, 8:07 PM
  • naumova

We present a new MPF reconstruction algorithm eliminating the need in B1 correction at the ISMRM Virtual Conference. The full abstract and video presentation are available to the Meeting participants: https://www.ismrm.org/20/program_files/O64.htm

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Software for MPF mapping released
  • Jul 8, 2020, 12:20 AM
  • yarnykh

Users can download the first public version of our software for reconstruction of MPF, T1, R1, and proton density maps from this website.

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Scan–Rescan Repeatability and Impact of B0 and B1 Field Nonuniformity Corrections in Single‐Point Whole‐Brain Macromolecular Proton Fraction Mapping
  • Jun 22, 2020, 9:29 PM
  • admin

A new article validating a substantial simplification of the fast MPF mapping protocols: B0 mapping can be omitted in the majority of applications. It also shows that B1 mapping also can be skipped in lower magnetic fields (1.5 T and below).

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MS patients’ symptom severity linked to gray matter myelin loss
  • Jun 22, 2020, 8:45 PM
  • admin

An earlier study published in Radiology showed a promise of MPF mapping in multiple sclerosis.

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