Macromolecular Proton Fraction (MPF): Quantitative Myelin Mapping Technique for Neuroscience

News

Featured Article in the Journal of Neuroscience
  • Sep 2, 2023, 6:07 AM
  • yarnykh

Researchers from the University of Washington Institute for Learning & Brain Sciences employed MPF mapping to assess correlations between myelination and language experience in two-year-old children.

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Member-Initiated Tutorial at ISMRM 2022 in London - Macromolecular Proton Fraction (MPF) from Scratch: Practical Guide on Protocols & Software Tools
  • May 7, 2022, 8:28 AM
  • yarnykh

Our team with colleagues from the University of Wisconsin–Madison and Polytechnique Montreal will carry out a two-hour teaching session on the software tools and protocol design for MPF mapping.

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Review article specifically focused on MPF as a myelin biomarker
  • May 7, 2022, 7:35 AM
  • yarnykh

A comprehensive review of MPF mapping methods, histological validation studies, and MPF applications was published in the Frontiers in Neuroscience.

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New simple preprocessing tool for Bruker users
  • Jun 28, 2021, 2:05 AM
  • yarnykh

A simple batch converter for Bruker ParaVision images with accurate rescaling is available for download (executable and source code). Please visit our software page.

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MPF mapping Symposium at ISMRM 2021 went a great success
  • Jun 27, 2021, 7:53 AM
  • yarnykh

Recollection of the first dedicated international MPF mapping Symposium at ISMRM 2021: 299 participants from 25 countries.

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C++ software codes for reconstruction of MPF, T1, R1, and proton density maps released
  • May 18, 2021, 1:48 AM
  • yarnykh

Users can download source codes of our reconstruction software. A new version of software (v.1.1) with added functionality of B1 map rescaling is available.

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First large-scale neuroscience study based on the fast MPF mapping method published in Neuroimage
  • May 17, 2021, 10:30 PM
  • yarnykh

Based on brain MPF maps from 146 adolescents, the protracted myelin development in cortical gray matter and subcortical white matter has been characterized as the function of age, gender, and puberty status.

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ISMRM “Live Q&A session” on Wednesday, August 12, 2020, 14:30 - 15:15 UTC.
  • Aug 9, 2020, 8:07 PM
  • naumova

We present a new MPF reconstruction algorithm eliminating the need in B1 correction at the ISMRM Virtual Conference. The full abstract and video presentation are available to the Meeting participants: https://www.ismrm.org/20/program_files/O64.htm

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